By default, we've set it up so that it matches our FTDI cables. The 6th pin is RTS, the power wire is +5V and the signal levels are 3.3V
(they are 5V compliant, and should work in the vast majority of 3.3V and 5V signal systems). Works excellently with any Arduino, ESP8266, ESP32 or any other microcontroller that uses an 'FTDI port' for communications and upload.
You can also purchase a 6-pin extension cable from us, which will let you rearrange the wire order.
There's also a full collection of all the modem control pins you may need on the side, in case you need the DTR, RI, DSR, etc. pins.

Each order comes with a fully assembled and tested board. We give you a right-angle socket header and some male header strip.
You can solder in the socket header on the edge to make it 'FTDI-like' or solder the male headers in to plug it into a breadboard and get access to all the pins.

For Mac, Linux you won't need a driver. For Windows, it will automatically grab the driver from Windows Update.